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Tg(Tbx1-cre)1Joe
Transgene Detail
Nomenclature
Symbol: Tg(Tbx1-cre)1Joe
Name: transgene insertion 1, Jonathan A Epstein
MGI ID: MGI:3037834
Synonyms: Tbx1-Cre, Tbx1-enCre
Transgene: Tg(Tbx1-cre)1Joe  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsSequence encoding cre recombinase was adjoined to mouse Tbx1 promoter sequence that extended 16 kb from the start codon and included the proximal promoter and three conserved enhancer regions. The expression pattern of cre recombinase recapitulated that of Tbx1, with expression observed in the mesenchyme, otic vesicle, and somites during development. (J:88814)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tbx1     Summary of all recombinase alleles driven by Tbx1.
 

Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:88814 Brown CB, et al., Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse. Dev Biol. 2004 Mar 1;267(1):190-202
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory