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Idd18C57BL/6
QTL Variant Detail
Nomenclature
QTL variant: Idd18C57BL/6
Name: insulin dependent diabetes susceptibility 18; C57BL/6
MGI ID: MGI:3036823
QTL: Idd18  Location: unknown  Genetic Position: Chr3, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers resistance to insulin dependent diabetes compared to NOD.
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes
Idd10 and Idd18 interact to promote disease resistance. Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd18 confers significantly increased resistance to type 1 diabetes.
References
Original:  J:46659 Podolin PL, et al., Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3. Mamm Genome. 1998 Apr;9(4):283-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory