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Napatm1Caw
Targeted Allele Detail
Summary
Symbol: Napatm1Caw
Name: N-ethylmaleimide sensitive fusion protein attachment protein alpha; targeted mutation 1, Christopher A Walsh
MGI ID: MGI:3036672
Gene: Napa  Location: Chr7:15832383-15851900 bp, + strand  Genetic Position: Chr7, 8.74 cM
Alliance: Napatm1Caw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:88495
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targeting vector pKO-Napa replaces coding exons 2 and 3 with BetaGal and a neomycin cassette. This results in a translational frameshift and premature termination in exon 4. (J:88495)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Napa Mutation:  16 strains or lines available
References
Original:  J:88495 Chae TH, et al., The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory