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Targeted Allele Detail
Symbol: Elk4tm1Rtr
Name: ELK4, member of ETS oncogene family; targeted mutation 1, Richard Treisman
MGI ID: MGI:3036598
Synonyms: SAP-1-
Gene: Elk4  Location: Chr1:132007607-132032612 bp, + strand  Genetic Position: Chr1, 57.24 cM, cytoband E3-G
Germline Transmission:  Earliest citation of germline transmission: J:88515
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA portion of exon 1 and all of exons 2 and 3 were replaced with an IRES-lacZ-neo cassette. Transcript was undetected in the thymi of homozygous mutant mice by RNAse protection. lacZ expression was not reported. (J:88515)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Elk4 Mutation:  8 strains or lines available
Original:  J:88515 Costello PS, et al., Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection. Nat Immunol. 2004 Mar;5(3):289-98
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory