About   Help   FAQ
Syptm1Leu
Targeted Allele Detail
Summary
Symbol: Syptm1Leu
Name: synaptophysin; targeted mutation 1, Rudolf E Leube
MGI ID: MGI:3033781
Synonyms: SPH-
Gene: Syp  Location: ChrX:7504819-7519495 bp, + strand  Genetic Position: ChrX, 3.44 cM, cytoband A-D
Alliance: Syptm1Leu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30488
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted into exon 2. Northern blot analysis on RNA derived from brain tissue of homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:30488)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syp Mutation:  22 strains or lines available
References
Original:  J:30488 Eshkind LG, et al., Mice lacking synaptophysin reproduce and form typical synaptic vesicles. Cell Tissue Res. 1995 Dec;282(3):423-33
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory