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Syptm1Leu
Targeted Allele Detail
Nomenclature
Symbol: Syptm1Leu
Name: synaptophysin; targeted mutation 1, Rudolf E Leube
MGI ID: MGI:3033781
Synonyms: SPH-
Gene: Syp  Location: ChrX:7638471-7653256 bp, + strand  Genetic Position: ChrX, 3.44 cM, cytoband A-D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30488
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted into exon 2. Northern blot analysis on RNA derived from brain tissue of homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:30488)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syp Mutation:  17 strains or lines available
References
Original:  J:30488 Eshkind LG, et al., Mice lacking synaptophysin reproduce and form typical synaptic vesicles. Cell Tissue Res. 1995 Dec;282(3):423-33
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory