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Fasltm1.1Lest
Targeted Allele Detail
Nomenclature
Symbol: Fasltm1.1Lest
Name: Fas ligand (TNF superfamily, member 6); targeted mutation 1.1, Matthieu Levi-Strauss
MGI ID: MGI:3032864
Synonyms: FasL-
Gene: Fasl  Location: Chr1:161780689-161788495 bp, - strand  Genetic Position: Chr1, 69.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87990
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe neomycin selection cassette and the entire coding region were deleted from Tnfsf6tm1Lest by cre-mediated recombination of a flanking loxP sites. (J:87990)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fasl Mutation:  21 strains or lines available
References
Original:  J:87990 Karray S, et al., Complete loss of Fas ligand gene causes massive lymphoproliferation and early death, indicating a residual activity of gld allele. J Immunol. 2004 Feb 15;172(4):2118-25
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/19/2017
MGI 6.10
The Jackson Laboratory