Rgma^tm1Arbr
Targeted Allele Detail

Summary

• Symbol: Rgma^tm1Arbr
• Name: repulsive guidance molecule family member A; targeted mutation 1, Silvia Arber
• MGI ID: MGI:3029714
• Synonyms: mRGMNA^-
• Gene: Rgma Location: Chr7:73025268-73069647 bp, + strand Genetic Position: Chr7, 41.85 cM
• Alliance: Rgma^tm1Arbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87768
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The exon containing the start codon and encoding the signal peptide was replaced with a neomcyin selection inserted by homologous recombination. (J:87768)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgma Mutation: 26 strains or lines available

References

• Original: J:87768 Niederkofler V, et al., Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18
• All: 1 reference(s)