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Fhl2tm1Chen
Targeted Allele Detail
Summary
Symbol: Fhl2tm1Chen
Name: four and a half LIM domains 2; targeted mutation 1, Ju Chen
MGI ID: MGI:3029431
Synonyms: Fhl2tm1Juc, SLIM3-
Gene: Fhl2  Location: Chr1:43162234-43236144 bp, - strand  Genetic Position: Chr1, 22.33 cM
Alliance: Fhl2tm1Chen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64807
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ gene and neomycin selection cassette were inserted into the endogenous gene such that the lacZ gene would be expressed under the control of the endogenous promoter elements. Northern blot analysis confirmed that no wild-type transcript was expressed from this allele. (J:64807)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fhl2 Mutation:  16 strains or lines available
References
Original:  J:64807 Chu PH, et al., FHL2 (SLIM3) is not essential for cardiac development and function. Mol Cell Biol. 2000 Oct;20(20):7460-2
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory