Tead1^Gt(ROSA5)Sor
Gene trapped Allele Detail

Summary

• Symbol: Tead1^Gt(ROSA5)Sor
• Name: TEA domain family member 1; gene trap ROSA5, Philippe Soriano
• MGI ID: MGI:3028949
• Synonyms: ROSA5, Tead1^Gt(ROSA)5Sor, Tead1^{Gt(ROSABetageo)5Sor}
• Gene: Tead1 Location: Chr7:112278563-112505991 bp, + strand Genetic Position: Chr7, 58.8 cM, cytoband F2
• Alliance: Tead1^Gt(ROSA5)Sor page

Mutation origin

• Mutant Cell Line: FHCRC-GT-ROSA5
• Germline Transmission: Earliest citation of germline transmission: J:20882
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSABetageo
• Mutation details: The ROSA Beta-geo retroviral gene trap vector was inserted 5' to the translation initiation site. RT-PCR analysis indicated that wild-type mRNA transcripts were not formed. (J:20882)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-ROSA5	CG465836 ; (MGI Seq Detail)	5' RACE	Chr7:112278794-112278932 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  473 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tead1 Mutation: 274 strains or lines available

References

• Original: J:20882 Chen Z, et al., Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev. 1994 Oct 1;8(19):2293-301
• All: 1 reference(s)