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Cited1tm1Dunw
Targeted Allele Detail
Nomenclature
Symbol: Cited1tm1Dunw
Name: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1; targeted mutation 1, Sally L Dunwoodie
MGI ID: MGI:3028946
Synonyms: Cited1neo
Gene: Cited1  Location: ChrX:102247381-102252181 bp, - strand  Genetic Position: ChrX, 45.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87595
Parent Cell Line:  E14.2 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was deleted via cre-mediated recombination of the loxP sites inserted by homologous recombination. Although the targeting vector included an frt-flanked neo cassette and sequence encoding GFP, GFP expression was undetected. Sequence analysis of the targeted locus identified a single base insertion, resulting in a frameshift mutation in the inserted sequence. (J:87595)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cited1 Mutation:  4 strains or lines available
References
Original:  J:87595 Rodriguez TA, et al., Cited1 is required in trophoblasts for placental development and for embryo growth and survival. Mol Cell Biol. 2004 Jan;24(1):228-44
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory