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Slc1a6tm1Dbe
Targeted Allele Detail
Nomenclature
Symbol: Slc1a6tm1Dbe
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6; targeted mutation 1, Dwight E Bergles
MGI ID: MGI:3027689
Synonyms: EAAT4-
Gene: Slc1a6  Location: Chr10:78780496-78814825 bp, + strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87447
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 7, which encodes the sixth transmembrane segment, was replaced with a neomycin resistance gene. Lack of transcript was demonstrated by PCR and absence of protein was confirmed by Western blot analysis and immunocytochemistry. (J:87447)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc1a6 Mutation:  25 strains or lines available
References
Original:  J:87447 Huang YH, et al., Climbing fiber activation of EAAT4 transporters and kainate receptors in cerebellar Purkinje cells. J Neurosci. 2004 Jan 7;24(1):103-11
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory