About   Help   FAQ
Ceacam1Hv2-s
Spontaneous Allele Detail
Nomenclature
Symbol: Ceacam1Hv2-s
Name: carcinoembryonic antigen-related cell adhesion molecule 1; hepatitis virus (MHV-4) susceptibility
MGI ID: MGI:3027072
Synonyms: Ceacam1a
Gene: Ceacam1  Location: Chr7:25161132-25177028 bp, - strand  Genetic Position: Chr7, 13.84 cM
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
 
Mutation detailsThis allele determines susceptibility to infection by the JHM and A59 strains of mouse hepatitis virus MHV-4, and is found in the strains A/J, C57BL/10, BALB/c, NZB, DBA/2, AKR/J, CBA/J, C3H/He, and SWR and most other inbred strains. (J:3241, J:92495)
Inheritance:    Not Specified
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ceacam1 Mutation:  29 strains or lines available
Notes

Previously called Mhv-1, Hv2. This locus controls resistance of neurons and macrophages to infection by the JHM and A59 strains of mouse hepatitis virus MHV-4. The allele Ceacam1Hv2-r determines resistance and has been found only in the SJL/J strain; the strains A/J, C57BL/10, BALB/c, NZB, DBA/2, AKR/J, CBA/J, C3H/He, and SWR are all susceptible to infection (Ceacam1Hv2-s. Heterozygotes are fully susceptible (J:6451, J:14870, J:7456).

References
Original:  J:701 Dveksler GS, et al., Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J Virol. 1991 Dec;65(12):6881-91
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/07/2021
MGI 6.17
The Jackson Laboratory