About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 8:00 AM ET Wed, September 18.
Targeted Allele Detail
Symbol: Efnb2tm4Kln
Name: ephrin B2; targeted mutation 4, Rudiger Klein
MGI ID: MGI:3026687
Synonyms: ephrinB2fl, ephrinB2lx
Gene: Efnb2  Location: Chr8:8617434-8661242 bp, - strand  Genetic Position: Chr8, 3.42 cM
Germline Transmission:  Earliest citation of germline transmission: J:87398
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA 2.2 kb genomic fragment including exon 2 was flanked by single loxP sites. An frt-flanked neo cassette included in the targeting vector was excised via FLP-mediated recombination. (J:87398)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Efnb2 Mutation:  21 strains or lines available
Original:  J:87398 Grunwald IC, et al., Hippocampal plasticity requires postsynaptic ephrinBs. Nat Neurosci. 2004 Jan;7(1):33-40
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory