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Artm1.1Chc
Targeted Allele Detail
Nomenclature
Symbol: Artm1.1Chc
Name: androgen receptor; targeted mutation 1.1, Chawnshang Chang
MGI ID: MGI:2687199
Synonyms: AR-, ARKO, GARKO
Gene: Ar  Location: ChrX:98149721-98323215 bp, + strand  Genetic Position: ChrX, 42.82 cM
Immunostaining of androgen receptor and histological analysis of testes of Artm1.1Chc/Y mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81789
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe loxP flanked region including exon 2 was excised from Artm1Chc via cre mediated recombination. Exon 2 encodes the second zinc finger of the DNA-binding domain. (J:81789)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ar Mutation:  13 strains or lines available
References
Original:  J:81789 Yeh S, et al., Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13498-503
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory