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Pomctm2Ute
Targeted Allele Detail
Nomenclature
Symbol: Pomctm2Ute
Name: pro-opiomelanocortin-alpha; targeted mutation 2, Ute Hochgeschwender
MGI ID: MGI:2687084
Gene: Pomc  Location: Chr12:3954951-3960618 bp, + strand  Genetic Position: Chr12, 1.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57503
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pomc Mutation:  8 strains or lines available
References
Original:  J:57503 Yaswen L, et al., Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin [see comments]. Nat Med. 1999 Sep;5(9):1066-70
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory