About   Help   FAQ
Hoxa3tm1(cre)Moon
Targeted Allele Detail
Summary
Symbol: Hoxa3tm1(cre)Moon
Name: homeobox A3; targeted mutation 1, Anne M Moon
MGI ID: MGI:2686838
Synonyms: A3cre, Hoxa3Cre, Hoxa3-Ires-Cre
Gene: Hoxa3  Location: Chr6:52146042-52190316 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa3tm1(cre)Moon page
Abnormal caudal body formation in Bmp4tm4Blh/Bmp4+ Bmp7tm1.1Dgra/Bmp7tm1.1Dgra Hoxa3tm1(cre)Moon/Hoxa3+ embryos

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87304
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Hoxa3tm1(cre)Moon expression driven by 1 gene
 
Mutation detailsAn IRES-cre cassette followed by an frt-flanked neomycin gene was targeted downstream of the Hoxa3 coding region. The cassette was inserted 4 bp 3' of the stop codon and upstream of the polyadenylation signal. (J:87304)
Recombinase
activity
Activity:
Loading...
Driver: Hoxa3 (mouse)
Summary of all recombinase alleles driven by Hoxa3.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 60 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxa3 Mutation:  24 strains or lines available
References
Original:  J:87304 Macatee TL, et al., Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development. 2003 Dec;130(25):6361-74
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory