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Chemically induced Allele Detail
Symbol: Twist1Pas
Name: twist basic helix-loop-helix transcription factor 1; Pasteur
MGI ID: MGI:2684436
Synonyms: Pdt
Gene: Twist1  Location: Chr12:33957671-33959817 bp, + strand  Genetic Position: Chr12, 14.81 cM, cytoband B-C1
Polydactyly in the right hindlimb of Twist1Pas/Twist1+ mice

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  BTBR
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
Mutation detailsThis ENU induced mutation was found to be alleleic through complementation analysis with a known allele at the Twist1 locus. No sequence alteration was found in the coding region of the gene. A decrease in transcript was noted by in situ hybridization. (J:86815)
Inheritance:    Semidominant
View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Twist1 Mutation:  9 strains or lines available
Original:  J:8293 Shedlovsky A, et al., Induction of recessive lethal mutations in the T/t-H-2 region of the mouse genome by a point mutagen. Genet Res. 1986 Apr;47(2):135-42
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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