About   Help   FAQ
Kltm1Yin
Targeted Allele Detail
Nomenclature
Symbol: Kltm1Yin
Name: klotho; targeted mutation 1, Yo-ichi Nabeshima
MGI ID: MGI:2684400
Synonyms: kl-
Gene: Kl  Location: Chr5:150952607-150993809 bp, + strand  Genetic Position: Chr5, 89.77 cM, cytoband G3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86859
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 1 was disrupted by homologous recombination of a targeting vector. Protein was undetected in homozygous mutant mice. (J:86859)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kl Mutation:  4 strains or lines available
References
Original:  J:86859 Tsujikawa H, et al., Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol. 2003 Dec;17(12):2393-403
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/12/2015
MGI 5.21
The Jackson Laboratory