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Akap4tm1Eddy
Targeted Allele Detail
Nomenclature
Symbol: Akap4tm1Eddy
Name: A kinase (PRKA) anchor protein 4; targeted mutation 1, Edward M Eddy
MGI ID: MGI:2684287
Gene: Akap4  Location: ChrX:7067519-7078609 bp, + strand  Genetic Position: ChrX, 3.17 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86899
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 6 was deleted via cre-mediated recombination of flanking loxP sites. Protein was undetected in homozygous mice by Western blot analysis of testis tissue and epididymal sperm. (J:86899)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akap4 Mutation:  1 strain or line available
References
Original:  J:86899 Miki K, et al., Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility. Dev Biol. 2002 Aug 15;248(2):331-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory