Jade1^{Gt(pGT1,2,3)E148Vw}
Gene trapped Allele Detail

Summary

• Symbol: Jade1^{Gt(pGT1,2,3)E148Vw}
• Name: jade family PHD finger 1; gene trap E148, Valerie Wilson
• MGI ID: MGI:2682601
• Synonyms: mJade1^gtE148ISCR
• Gene: Jade1 Location: Chr3:41510169-41571299 bp, + strand Genetic Position: Chr3, 19.88 cM
• Alliance: Jade1^{Gt(pGT1,2,3)E148Vw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:86562
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The endogenous locus was disrupted by the insertion of a gene trap vector into intron 3. The vector consisted of an engrailed 2 intron, splice acceptor site, beta-geo, and polyadenylation signal. Northern blot and RT-PCR analyses of mutant mice identified truncated transcript encoding the first 47 residues. Wild-type transcript was undetected in homozygous mutant mice. (J:86562)

Expression

In Mice Carrying this Mutation:

60 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jade1 Mutation: 97 strains or lines available

References

• Original: J:86562 Tzouanacou E, et al., Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. Mol Cell Biol. 2003 Dec;23(23):8553-2
• All: 1 reference(s)