About   Help   FAQ
EgfrMhdadsk5
Chemically induced Allele Detail
Summary
Symbol: EgfrMhdadsk5
Name: epidermal growth factor receptor; Martin Hrabe de Angelis dark skin 5
MGI ID: MGI:2682255
Synonyms: EgfrDsk5
Gene: Egfr  Location: Chr11:16702203-16868158 bp, + strand  Genetic Position: Chr11, 9.41 cM, cytoband A1-A4
Alliance: EgfrMhdadsk5 page
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation was identified as an T to A transversion causing a missense mutation that predicts a Leu863Gln substitution in tyrosine kinase domain. (J:81301)
Inheritance:    Dominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egfr Mutation:  66 strains or lines available
References
Original:  J:81301 Fitch KR, et al., Genetics of dark skin in mice. Genes Dev. 2003 Jan 15;17(2):214-28
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
11/22/2022
MGI 6.22
The Jackson Laboratory