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Targeted Allele Detail
Symbol: Artm1Ska
Name: androgen receptor; targeted mutation 1, Shigeaki Kato
MGI ID: MGI:2681507
Synonyms: ARKO
Gene: Ar  Location: ChrX:98149721-98323215 bp, + strand  Genetic Position: ChrX, 42.82 cM
Germline Transmission:  Earliest citation of germline transmission: J:85484
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was introduced downstream. Cre mediated excision results in disruption of the gene. No mRNA transcripts were detected in the brain by Northern blot analysis and RT-PCR. Protein product was undetectable immunologically. This allele was generated from Artm2Ska. (J:85484, J:88153)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ar Mutation:  17 strains or lines available
Original:  J:85484 Matsumoto T, et al., Androgen receptor functions from reverse genetic models. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):95-9
All:  19 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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