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Osmrtm1Mtan
Targeted Allele Detail
Nomenclature
Symbol: Osmrtm1Mtan
Name: oncostatin M receptor; targeted mutation 1, Minoru Tanaka
MGI ID: MGI:2680723
Synonyms: OSMR-, OSMRbeta-
Gene: Osmr  Location: Chr15:6813577-6874969 bp, - strand  Genetic Position: Chr15, 3.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86261
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA cassette containing lacZ and neo was inserted at the start codon of the endogenous locus. Transcript was undetected in homozygous mutant mice by Northern blot analysis of lung RNA. (J:86261)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Osmr Mutation:  36 strains or lines available
References
Original:  J:86261 Tanaka M, et al., Targeted disruption of oncostatin M receptor results in altered hematopoiesis. Blood. 2003 Nov 1;102(9):3154-62
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory