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Gabrg2tm2Lusc
Targeted Allele Detail
Nomenclature
Symbol: Gabrg2tm2Lusc
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2; targeted mutation 2, Bernhard Luscher
MGI ID: MGI:2680624
Synonyms: fgamma2
Gene: Gabrg2  Location: Chr11:41910203-42000857 bp, - strand  Genetic Position: Chr11, 24.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86221
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 8 was left flanked by single loxP sites after an frt flanked neo cassette was excised via Flp-mediated recombination. A single flp site was left immediately downstream of the 3' loxP site. (J:86221)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabrg2 Mutation:  5 strains or lines available
References
Original:  J:86221 Schweizer C, et al., The gamma2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses. Mol Cell Neurosci. 2003 Oct;24(2):442-50
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory