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Pak5tm1Amin
Targeted Allele Detail
Nomenclature
Symbol: Pak5tm1Amin
Name: p21 (RAC1) activated kinase 5; targeted mutation 1 Audrey Minden
MGI ID: MGI:2679653
Synonyms: PAK5-
Gene: Pak5  Location: Chr2:136081104-136387967 bp, - strand  Genetic Position: Chr2, 67.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85956
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant brain extracts. (J:85956)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pak5 Mutation:  25 strains or lines available
References
Original:  J:85956 Li X, et al., Targeted disruption of the gene for the PAK5 kinase in mice. Mol Cell Biol. 2003 Oct;23(20):7134-42
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory