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Cplx2tm1Rmnd
Targeted Allele Detail
Nomenclature
Symbol: Cplx2tm1Rmnd
Name: complexin 2; targeted mutation 1, Christian Rosenmund
MGI ID: MGI:2679626
Synonyms: CPX II-
Gene: Cplx2  Location: Chr13:54371349-54383917 bp, + strand  Genetic Position: Chr13, 28.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86365
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll three coding exons were replaced by a neomycin cassette. Western blot analysis of adult brains demonstrated the abolition of protein product expression. (J:86365)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cplx2 Mutation:  11 strains or lines available
References
Original:  J:86365 Reim K, et al., Complexins regulate a late step in Ca2+-dependent neurotransmitter release. Cell. 2001 Jan 12;104(1):71-81
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory