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Smad5tm1.1Huy
Targeted Allele Detail
Nomenclature
Symbol: Smad5tm1.1Huy
Name: SMAD family member 5; targeted mutation 1.1, Danny Huylebroeck
MGI ID: MGI:2679443
Synonyms: Smad5fldeltaE2
Gene: Smad5  Location: Chr13:56703010-56742377 bp, + strand  Genetic Position: Chr13, 30.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86157
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was deleted via cre mediated recombination, leaving a single loxP site in its place. Exon 2 contains the translational start codon and approximately one-third of the protein coding sequence. (J:86157)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad5 Mutation:  6 strains or lines available
References
Original:  J:86157 Umans L, et al., Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse. Genesis. 2003 Sep;37(1):5-11
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory