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Smad5tm1Huy
Targeted Allele Detail
Nomenclature
Symbol: Smad5tm1Huy
Name: SMAD family member 5; targeted mutation 1, Danny Huylebroeck
MGI ID: MGI:2679441
Synonyms: Smad5flE2, Smad5flox, Smad5fx, Smad5fx(exon2)
Gene: Smad5  Location: Chr13:56703010-56742377 bp, + strand  Genetic Position: Chr13, 30.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86157
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by single loxP sites. Exon 2 contains the translational start codon and approximately one-third of the protein coding sequence. (J:86157)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad5 Mutation:  8 strains or lines available
References
Original:  J:86157 Umans L, et al., Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse. Genesis. 2003 Sep;37(1):5-11
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory