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Targeted Allele Detail
Symbol: Arnttm1.1Gonz
Name: aryl hydrocarbon receptor nuclear translocator; targeted mutation 1.1, Frank Gonzalez
MGI ID: MGI:2679359
Synonyms: Arntflox
Gene: Arnt  Location: Chr3:95434388-95497240 bp, + strand  Genetic Position: Chr3, 40.74 cM
Germline Transmission:  Earliest citation of germline transmission: J:85934
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsExon 6 was left flanked by single loxP sites after the floxed neo cassette was removed from intron 5 of Arnttm1Gonz via cre mediated recombination in the germline. (J:85934)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:  15 strains or lines available
Original:  J:85934 Tomita S, et al., T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. J Immunol. 2003 Oct 15;171(8):4113-20
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory