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Tg(Tnnt2-cre)5Blh
Transgene Detail
Nomenclature
Symbol: Tg(Tnnt2-cre)5Blh
Name: transgene insertion 5, Brigid L Hogan
MGI ID: MGI:2679081
Synonyms: cTntCre, cTnt-Cre, Tnnt2-Cre, TNT-Cre
Transgene: Tg(Tnnt2-cre)5Blh  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsSequence encoding cre recombinase was adjoined to the rat troponin T2 promoter. The promoter drove expression of cre recombinase in the cardiomyocyte lineage beginning at E7.5. Expression was observed in all myocardium at E10.5. (J:86001, J:175042)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tnnt2 (rat) Summary of all recombinase alleles driven by Tnnt2. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 74 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:86001 Jiao K, et al., An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 2003 Oct 1;17(19):2362-7
All:  78 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory