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Ikbkgtm1.1Mpa
Targeted Allele Detail
Nomenclature
Symbol: Ikbkgtm1.1Mpa
Name: inhibitor of kappaB kinase gamma; targeted mutation 1.1, Manolis Pasparakis
MGI ID: MGI:2679024
Synonyms: NemoF, NemoFL
Gene: Ikbkg  Location: ChrX:74393290-74453854 bp, + strand  Genetic Position: ChrX, 38.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63055
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 2 was left flanked by single loxP sites in introns 1 and 2. (J:63055)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ikbkg Mutation:  11 strains or lines available
References
Original:  J:63055 Schmidt-Supprian M, et al., NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol Cell. 2000 Jun;5(6):981-92
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory