Caml^tm1Rjb
Targeted Allele Detail

Summary

• Symbol: Caml^tm1Rjb
• Name: calcium modulating ligand; targeted mutation 1, Richard J Bram
• MGI ID: MGI:2678819
• Synonyms: CAML^-
• Gene: Caml Location: Chr13:55770818-55780224 bp, + strand Genetic Position: Chr13, 30.06 cM
• Alliance: Caml^tm1Rjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85708
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All of exon 1 and a 5' portion of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant ES cells. (J:85708)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Caml Mutation: 25 strains or lines available

References

• Original: J:85708 Tran DD, et al., CAML is required for efficient EGF receptor recycling. Dev Cell. 2003 Aug;5(2):245-56
• All: 2 reference(s)