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Unc5crcmTg(Tert)5Hwl
Transgenic Allele Detail
Summary
Symbol: Unc5crcmTg(Tert)5Hwl
Name: unc-5 netrin receptor C; transgene insertion 5, Han-Woong Lee
MGI ID: MGI:2678074
Synonyms: Unc5crcmTgN(Tert)5Hwl
Gene: Unc5c  Location: Chr3:141171360-141540685 bp, + strand  Genetic Position: Chr3, 65.57 cM
Alliance: Unc5crcmTg(Tert)5Hwl page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic
Mutation:    Insertion
 
Mutation detailsA 5.6 kb transgenic construct containing cDNA encoding telomerase reverse transcriptase under the control of the chicken beta-actin promoter randomly inserted into intron 1 of Unc5c. The insertion deleted approximately 50 kb of intron 1. While Unc5c transcript was detected in the testes of homozygous mutant mice, transcript was undetected in the cerebellum, lung, spleen, or ovaries. (J:85446)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Unc5c Mutation:  61 strains or lines available
References
Original:  J:85446 Choi YS, et al., Insertional mutation in the intron 1 of Unc5h3 gene induces ataxic, lean and hyperactive phenotype in mice. Exp Anim. 2003 Jul;52(4):273-83
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory