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Bc1tm1Jbro
Targeted Allele Detail
Nomenclature
Symbol: Bc1tm1Jbro
Name: brain cytoplasmic RNA 1; targeted mutation 1, Jurgen Brosius
MGI ID: MGI:2677614
Gene: Bc1  Location: Chr7:144468207-144468360 bp, + strand  Genetic Position: Chr7, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85467
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe endogenous gene was replaced with a neomycin selection cassette inserted by homologous recombination. Northern blot analysis confirmed the absence of transcript in homozygous mutant mice. (J:85467)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bc1 Mutation:  1 strain or line available
References
Original:  J:85467 Skryabin BV, et al., Neuronal untranslated BC1 RNA: targeted gene elimination in mice. Mol Cell Biol. 2003 Sep;23(18):6435-41
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory