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Stk11tm1.1Jish
Targeted Allele Detail
Nomenclature
Symbol: Stk11tm1.1Jish
Name: serine/threonine kinase 11; targeted mutation 1.1, Kou-ichi Jishage
MGI ID: MGI:2676546
Synonyms: Lkb1-
Gene: Stk11  Location: Chr10:80115803-80130682 bp, + strand  Genetic Position: Chr10, 39.72 cM
Growth retardation, impaired embryo turning and small somites in Stk11tm1.1Jish/Stk11tm1.1Jish embryos

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77213
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Stk11tm1Jish and Stk11tm1.1Jish alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 16 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk11 Mutation:  5 strains or lines available
References
Original:  J:77213 Jishage K, et al., Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8903-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory