PitpnaGt(OST1152)Lex
Gene trapped Allele Detail
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Symbol: |
PitpnaGt(OST1152)Lex |
Name: |
phosphatidylinositol transfer protein, alpha; gene trap OST1152, Lexicon Genetics |
MGI ID: |
MGI:2676301 |
Synonyms: |
PITPalpha::neo/puro, PitpnaGt(VICTR20)1Vab |
Gene: |
Pitpna Location: Chr11:75478923-75519630 bp, + strand Genetic Position: Chr11, 45.92 cM
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Alliance: |
PitpnaGt(OST1152)Lex page
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Mutant Cell Line: |
OST1152 |
Germline Transmission: |
Earliest citation of germline transmission:
J:85204
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Parent Cell Line: |
Lex-1 (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: A gene trap vector consisting of LTR sites flanking a beta-geo cassette containing a splice acceptor and a PGK-puro cassette containing a splice donor integrated into intron 7. Truncated protein product was undetected by Western blot analysis of homozygous mutant mice.
(J:85204)
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Inheritance: |
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Recessive |
Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
541 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pitpna Mutation: |
37 strains or lines available
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Original: |
J:85204 Alb JG Jr, et al., Mice lacking phosphatidylinositol transfer protein-alpha exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia. J Biol Chem. 2003 Aug 29;278(35):33501-18 |
All: |
2 reference(s) |
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