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Bcl3tm1Rie
Targeted Allele Detail
Nomenclature
Symbol: Bcl3tm1Rie
Name: B cell leukemia/lymphoma 3; targeted mutation 1, Marc Riemann
MGI ID: MGI:2675475
Synonyms: Bcl-3-
Gene: Bcl3  Location: Chr7:19808462-19822770 bp, - strand  Genetic Position: Chr7, 9.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77049
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced sequence encompassing all of exons 3 through 5 and a portion of exon 6. Protein was undetected in homozygous mutant mice by Western blot analysis of spleen whole-cell protein extracts. (J:77049, J:144438)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl3 Mutation:  42 strains or lines available
References
Original:  J:77049 Paxian S, et al., Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Gastroenterology. 2002 Jun;122(7):1853-68
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory