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Rapgef1tm1Mats
Targeted Allele Detail
Nomenclature
Symbol: Rapgef1tm1Mats
Name: Rap guanine nucleotide exchange factor (GEF) 1; targeted mutation 1, Michiyuki Matsuda
MGI ID: MGI:2675465
Synonyms: C3G-
Gene: Rapgef1  Location: Chr2:29619720-29740978 bp, + strand  Genetic Position: Chr2, 20.32 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77323
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 15 and 16 were replaced with a neomycin selection cassette inserted by homologous recombination. (J:77323)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rapgef1 Mutation:  172 strains or lines available
References
Original:  J:77323 Ohba Y, et al., Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J. 2001 Jul 2;20(13):3333-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory