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Kcnc3tm1Echa
Targeted Allele Detail
Nomenclature
Symbol: Kcnc3tm1Echa
Name: potassium voltage gated channel, Shaw-related subfamily, member 3; targeted mutation 1, Emily Chan
MGI ID: MGI:2675309
Synonyms: Kv3.3-
Gene: Kcnc3  Location: Chr7:44590664-44604754 bp, + strand  Genetic Position: Chr7, 28.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71179
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe endogenous locus was disrupted by a PGK-neo cassette inserted by homologous recombination. The deleted region included the start codon. Protein was undetected by Western blot analysis of homozygous mutant mice. (J:71179)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnc3 Mutation:  13 strains or lines available
References
Original:  J:71179 Espinosa F, et al., Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. J Neurosci. 2001 Sep 1;21(17):6657-65
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory