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Tg(Hoxb7-cre)13Amc
Transgene Detail
Nomenclature
Symbol: Tg(Hoxb7-cre)13Amc
Name: transgene insertion 13, Andrew P McMahon
MGI ID: MGI:2675121
Synonyms: Hoxb7-Cre, HoxB7Cre, HoxB7/Cre
Transgene: Tg(Hoxb7-cre)13Amc  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA transgenic construct containing the 1.3Kb enhancer and promoter sequence upstream of the of mouse homeo box B7 gene, a human growth factor mini gene and the Cre coding sequence was injected into fertilized C57BL/6 mouse eggs. Cre recombinase expression is detected in the mesonephric duct as early as embryonic day 9.5, in the ureteric bud by embryonic day 10.25 and in all ureteric bud epithelial cells by embryonic day 12.5. Low levels of expression are detected in the dorsal root ganglia and the spinal cord. (J:79481, J:100575)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hoxb7     Summary of all recombinase alleles driven by Hoxb7. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:79481 Yu J, et al., Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov;129(22):5301-12
All:  82 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory