About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Targeted Allele Detail
Symbol: Gdf3tm1Zuk
Name: growth differentiation factor 3; targeted mutation 1, Martin M Matzuk
MGI ID: MGI:2673981
Gene: Gdf3  Location: Chr6:122605403-122610087 bp, - strand  Genetic Position: Chr6, 57.7 cM
Germline Transmission:  Earliest citation of germline transmission: J:143083
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsExon 2 was replaced with an Pgk1-HPRT cassette. The absence of transcript expression was confirmed by RT-PCR on spleen and white adipose tissue extracts. (J:143083)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdf3 Mutation:  28 strains or lines available
Original:  J:143083 Shen JJ, et al., Deficiency of Growth Differentiation Factor 3 Protects against Diet-Induced Obesity by Selectively Acting on White Adipose. Mol Endocrinol. 2009 Jan;23(1):113-23
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory