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Gdf3tm1Zuk
Targeted Allele Detail
Nomenclature
Symbol: Gdf3tm1Zuk
Name: growth differentiation factor 3; targeted mutation 1, Martin M Matzuk
MGI ID: MGI:2673981
Gene: Gdf3  Location: Chr6:122605403-122610087 bp, - strand  Genetic Position: Chr6, 57.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143083
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was replaced with an Pgk1-HPRT cassette. The absence of transcript expression was confirmed by RT-PCR on spleen and white adipose tissue extracts. (J:143083)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdf3 Mutation:  27 strains or lines available
References
Original:  J:143083 Shen JJ, et al., Deficiency of Growth Differentiation Factor 3 Protects against Diet-Induced Obesity by Selectively Acting on White Adipose. Mol Endocrinol. 2009 Jan;23(1):113-23
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory