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Targeted Allele Detail
Symbol: Pou3f3tm1Tno
Name: POU domain, class 3, transcription factor 3; targeted mutation 1, Tetsuo Noda
MGI ID: MGI:2673387
Synonyms: Brn-1-
Gene: Pou3f3  Location: Chr1:42695768-42703176 bp, + strand  Genetic Position: Chr1, 21.21 cM
Germline Transmission:  Earliest citation of germline transmission: J:84756
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation details70% (1.2 kb) of the endogenous coding region was replaced with a neo cassette. Gene product was undetected by Western blot analysis and electrophoresis mobility shift assay of homozygous mutant kidney and brain extracts, respectively. (J:84756)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f3 Mutation:  4 strains or lines available
Original:  J:84756 Nakai S, et al., Crucial roles of Brn1 in distal tubule formation and function in mouse kidney. Development. 2003 Oct;130(19):4751-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory