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Alg10bnse5
Chemically induced Allele Detail
Nomenclature
Symbol: Alg10bnse5
Name: asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase); neurological/sensory 5
MGI ID: MGI:2671810
Synonyms: Deaf1, nsem05Jus
Gene: Alg10b  Location: Chr15:90224311-90230554 bp, + strand  Genetic Position: Chr15, 45.07 cM
Outer hair cells of the cochlea are abnormal in Alg10bnse5/Alg10bnse5 mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Mutagenesis for Dev. Defects
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU-mutagenesis induced a point mutation that results in the amino acid substitution of serine for leucine at position 389 (L389S). (J:209766)
Inheritance:    Recessive
Identification of the mutation in the Alg10bnse5 allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Alg10b Mutation:  2 strains or lines available
References
Original:  J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory