Sema3f^tm1.2Ddg
Targeted Allele Detail

Summary

• Symbol: Sema3f^tm1.2Ddg
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1.2, David D Ginty
• MGI ID: MGI:2670663
• Synonyms: sema3F-
• Gene: Sema3f Location: Chr9:107558699-107587674 bp, - strand Genetic Position: Chr9, 58.91 cM, cytoband F2
• Alliance: Sema3f^tm1.2Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84687
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP flanked region extending from region extending from 4 kb upstream of exon 1 through 1 kb of intron 1, and including the FRT-flanked neo cassette, was excised from Sema3f^tm1Ddg via cre mediated recombination in the germline. Transcript was undetected by Northern blot analysis of homozygous mutant mice. (J:84687)

Expression

In Mice Carrying this Mutation:	46 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema3f Mutation: 41 strains or lines available

References

• Original: J:84687 Sahay A, et al., Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. J Neurosci. 2003 Jul 30;23(17):6671-80
• All: 18 reference(s)