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Targeted Allele Detail
Symbol: Sema3ftm1.2Ddg
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1.2, David D Ginty
MGI ID: MGI:2670663
Synonyms: sema3F-
Gene: Sema3f  Location: Chr9:107558699-107587674 bp, - strand  Genetic Position: Chr9, 58.91 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:84687
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP flanked region extending from region extending from 4 kb upstream of exon 1 through 1 kb of intron 1, and including the FRT-flanked neo cassette, was excised from Sema3ftm1Ddg via cre mediated recombination in the germline. Transcript was undetected by Northern blot analysis of homozygous mutant mice. (J:84687)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 46 assay results
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3f Mutation:  26 strains or lines available
Original:  J:84687 Sahay A, et al., Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. J Neurosci. 2003 Jul 30;23(17):6671-80
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory