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Targeted Allele Detail
Symbol: Sema3ftm1.1Ddg
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1.1, David D Ginty
MGI ID: MGI:2670662
Synonyms: sema3F C
Gene: Sema3f  Location: Chr9:107558699-107587674 bp, - strand  Genetic Position: Chr9, 58.91 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:84687
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsThe FRT flanked neo cassette located 4 kb upstream of exon 1 was removed from Sema3ftm1Ddg by in vivo FRT-mediated recombination. A region extending from 4 kb upstream of exon 1 through 1 kb of intron 1 remained flanked by single loxP sites. (J:84687)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3f Mutation:  26 strains or lines available
Original:  J:84687 Sahay A, et al., Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. J Neurosci. 2003 Jul 30;23(17):6671-80
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory