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Gnpattm1Just
Targeted Allele Detail
Nomenclature
Symbol: Gnpattm1Just
Name: glyceronephosphate O-acyltransferase; targeted mutation 1, Wilhelm W Just
MGI ID: MGI:2670461
Synonyms: DAPAT-
Gene: Gnpat  Location: Chr8:124863033-124890057 bp, + strand  Genetic Position: Chr8, 72.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84690
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 through 7 were replaced by a neomycin selection cassette. Protein was undetected by Western blot analysis of protein extracts obtained from the Harderian glands of homozygous mutant mice. (J:84690)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 14 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnpat Mutation:  24 strains or lines available
References
Original:  J:84690 Rodemer C, et al., Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum Mol Genet. 2003 Aug 1;12(15):1881-95
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory