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Cx3cr1tm1Litt
Targeted Allele Detail
Nomenclature
Symbol: Cx3cr1tm1Litt
Name: chemokine (C-X3-C motif) receptor 1; targeted mutation 1, Dan R Littman
MGI ID: MGI:2670351
Synonyms: CX3CR1-, CX3CR1EGFP, CX3CR1-EGFP, Cx3cr1gfp, CX3CR1GFP, CX3CR1-GFP, CX3CR-GFP
Gene: Cx3cr1  Location: Chr9:120048693-120068282 bp, - strand  Genetic Position: Chr9, 71.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84544
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  31 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Macular Degeneration, Geographic Atrophy, Dry Type (J:200877)

References
Original:  J:84544 Jung S, et al., Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol. 2000 Jun;20(11):4106-14
All:  210 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory