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Fam83gwly
Spontaneous Allele Detail
Nomenclature
Symbol: Fam83gwly
Name: family with sequence similarity 83, member G; wooly
MGI ID: MGI:2668878
Gene: Fam83g  Location: Chr11:61574917-61600777 bp, + strand  Genetic Position: Chr11, 37.96 cM
Wooly coat in Fam83gwly/Fam83gwly mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  NOD/ShiLtJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsA 955 bp deletion removes part of intron 2 and the splice acceptor site at the beginning of exon 3. This results in incorrect splicing and a premature stop codon leading to a truncated protein. The deletion overlaps with intron 10 of Slc5a10 on the opposite strand but does not affect splicing of that gene. (J:195478)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fam83g Mutation:  20 strains or lines available
References
Original:  J:84609 Ward-Bailey PF, et al., New mouse mutation on Chromosome 11 affecting hair texture. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory