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Tnfrsf9tm1Byk
Targeted Allele Detail
Nomenclature
Symbol: Tnfrsf9tm1Byk
Name: tumor necrosis factor receptor superfamily, member 9; targeted mutation 1, Byoung Kwon
MGI ID: MGI:2664914
Synonyms: 4-1BB-, 4-1BB-KO, CD137-
Gene: Tnfrsf9  Location: Chr4:150914562-150946102 bp, + strand  Genetic Position: Chr4, 81.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83996
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe gene was disrupted by insertion of a neomycin resistance cassette into the translation initiation site. (J:83996)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Tnfrsf9 Mutation:  13 strains or lines available
References
Original:  J:83996 Kwon BS, et al., Immune responses in 4-1BB (CD137)-deficient mice. J Immunol. 2002 Jun 1;168(11):5483-90
All:  46 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory